Cardiac amyloidosis is a serious, progressive, and underdiagnosed rare disease that leads to heart failure. In patients with cardiac amyloidosis, the heart walls become stiff, making it impossible for the left ventricle to properly relax and fill with blood, while at the same time hampering its ability to squeeze and pump blood out of the heart. Symptoms and comorbidities associated with cardiac amyloidosis, such as shortness of breath, knee pain, bilateral carpal tunnel syndrome, kidney disease, and gastrointestinal issues, can vary and seem unrelated, making diagnosis difficult.
