Category: Biomarker

August 4, 2020

Researchers from IRB Barcelona’s Genome Data Science Lab, led by the ICREA researcher Fran Supek, have discovered a new type of hypermutation called mutation fog, which can generate hundreds of mutations in every cell. Such mutations are widely distributed, but […]

August 4, 2020

A potentially safer, more effective chemotherapy treatment for patients with blood-related cancers, such as leukemia, who need a particular bone marrow transplant procedure is under study at the University of Arizona Health Sciences. The procedure is known as a haploidentical […]

August 4, 2020

Glioblastoma, the most widespread and lethal primary brain tumor in adults, is notoriously difficult to treat due to the surrounding lack of oxygen essential to the effectiveness of current treatment. A team of CNRS and University of Caen Normandie researchers […]

July 30, 2020

These risk factors, many of which are disproportionately apparent in African Americans, include heart health factors — such as high blood pressure, high cholesterol and diabetes — and social factors like education quality. According to the Alzheimer’s Association Alzheimer’s Disease […]

July 30, 2020

A vaccine for HER2-positive breast cancers that is being tested in a clinical trial at Duke Cancer Institute is part of an effective, two-drug strategy for enlisting the immune system to fight tumors, according to a Duke-led study in Clinical […]

July 29, 2020

For many years, the diagnosis of Alzheimer’s has been based on the characterization of amyloid plaques and tau tangles in the brain, typically after a person dies. An inexpensive and widely available blood test for the presence of plaques and […]

July 24, 2020

In a new study published in EBioMedicine, investigators from Brigham and Women’s Hospital conducted a systematic review and meta-analysis, analyzing data from more than 3,000 specimens to compare the three approaches. The team found that sputum testing detected the RNA […]

July 21, 2020

An international team of researchers has developed a non-invasive blood test that can detect whether an individual has one of five common types of cancers, four years before the condition can be diagnosed with current methods. The test detects stomach, […]

July 21, 2020

Age shows nowhere better than on the skin. The ravages of time on skin and the epidermal stem cells that differentiate to replenish its outer layer have been hypothesized, but there has been no method to evaluate their aging at […]

July 17, 2020

In a discovery that could advance the worldwide effort to limit the community spread of COVID-19 through robust contact tracing, researchers were able to identify recent COVID-19 cases using 25 microlitres of plasma from blood samples. The research team, led […]

July 17, 2020

Ewing sarcoma is a bone and soft tissue cancer that primarily affects children and adolescents. The discovery, made by scientists at the University of Toronto, relates to cell structures called nucleoli and a physical change they undergo called phase separation. […]

July 15, 2020

Immunotherapy drugs that harness the body’s own immune system to fight cancer have revolutionized the treatment of many cancers. They work by blocking checkpoint inhibitor proteins like PD1, removing the brakes from cancer-killing T cells in the immune system. However, […]

July 14, 2020

Preeclampsia is characterized by the elevated blood pressure of the mother, and the baby is often delivered preterm and smaller than usual. Although preeclampsia is cured by the delivery of the placenta, the mechanism of the disease has still remained […]

July 9, 2020

A characterising feature of SARS-CoV-2, the virus that causes COVID-19, is the protein spikes which cover the surface, which the virus uses to bind with and enter human cells. Analysing the structure of these spikes could provide clues about the […]

July 9, 2020

Natural killer (NK) cells, a type of immune cell, are known to limit metastasis by inducing the death of cancer cells. But metastases still form in patients, so there must be ways for cancer cells to escape. Using a novel […]