Category: Biomarker

January 19, 2021

A look at RNA tells us what our genes are telling our cells to do, and scientists say looking directly at the RNA of brain tumor cells appears to provide objective, efficient evidence to better classify a tumor and the […]

January 18, 2021

In an effort to address a major challenge when analyzing large single-cell RNA-sequencing datasets, researchers from The University of Texas MD Anderson Cancer Center have developed a new computational technique to accurately differentiate between data from cancer cells and the […]

January 15, 2021

Researchers have developed a DNA test to quickly identify secondary infections in COVID-19 patients, who have double the risk of developing pneumonia while on ventilation than non-COVID-19 patients. For patients with the most severe forms of COVID-19, mechanical ventilation is […]

January 13, 2021

In a new study, researchers at Karolinska Institutet in Sweden have used a urine test to identify and verify a patient’s type of asthma. The study, which has been published in the American Journal of Respiratory and Critical Care Medicine, […]

January 13, 2021

Completing cancer screening tests, such as mammograms, can be challenging for low-income people, who may face such challenges as lack of transportation or inability to take time off work. A team at Massachusetts General Hospital (MGH) explored the possibility of […]

January 11, 2021

A new study suggests a link between toxoplasma gondii (T. gondii) infection and the risk of glioma, a type of brain cancer, in adults. The report, appearing in the International Journal of Cancer, finds that people who have glioma are […]

January 5, 2021

The researchers believe their method could deliver a test that is not only fast but also sufficiently sensitive. The test does not require samples to be treated at high temperatures, and it can be performed using standard laboratory equipment, making […]

January 4, 2021

A cancer-specific L-type amino acid transporter 1 (LAT1) is highly expressed in cancer tissues. Inhibiting the function of LAT1 has been known to have anti-tumor effects, but there has been limited progress in the development of radionuclide therapy agents targeting […]

December 30, 2020

A majority of patients with colorectal cancer found at least one benefit from their diagnosis. (Fox Chase Cancer Center) Half of disruptions in ongoing clinical trials resulted from slow patient enrollment. (GlobalData) Laboratory studies suggested that a drug used to […]

December 28, 2020

Although rare, poly-ADP ribose polymerase (PARP) inhibitors were associated with an increased risk for myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), and occurred even after brief drug exposure, researchers reported. A systematic review and meta-analysis of 18 randomized clinical […]

December 23, 2020

A team of scientists from the Centers for Disease Control and Prevention, United States, recently conducted a study to evaluate the effectiveness of serial testing and isolation of healthcare personnel in nursing homes in preventing the transmission of severe acute […]

December 23, 2020

A newly developed compound starves cancer cells by attacking their “power plants” — the so-called mitochondria. The new compound prevents the genetic information within mitochondria from being read. Researchers from the Max Planck Institute for Biology of Ageing in Cologne, […]

December 22, 2020

Cold Spring Harbor Laboratory (CSHL) scientists have discovered a gene-regulating snippet of RNA that may contribute to the spread of many breast cancers. In animal experiments, the researchers could reduce the growth of metastatic tumors with a molecule designed to […]

December 18, 2020

Ground-breaking medical research in a consortium led by two UK universities will explore new ways to diagnose lung cancer earlier and save lives. The Universities of Southampton and Leeds have come together with healthcare, diagnostics and informatics companies to test […]

December 14, 2020

Scientists have long known that therapies that target the cancer-driving MAPK pathway are only effective in a handful of cancers with specific mutations in a cancer gene called BRAF, and these cancers that initially respond to the therapy often end […]