Category: Biomarker

March 18, 2019

There is an urgent need for an easily accessible preoperative test to predict postoperative liver function recovery and thereby determine the optimal timing of liver resection, particularly since the currently available methods are either costly, time-consuming or invasive. For several […]

March 12, 2019

The potential use of Growth Differentiation Factor 15 (GDF15) as a biomarker for the eye disease was first identified by a research team at Washington University. The marker is expected to improve treatment options for glaucoma patients. Glaucoma is characterised […]

March 4, 2019

People who are witnessed by a bed partner to have stopped breathing during sleep may have higher accumulations of an Alzheimer’s disease biomarker called tau in an area of the brain that helps with memory, according to a preliminary study […]

February 28, 2019

Antibodies are molecules produced by a human’s immune system to counteract bacteria and viruses. When a bacterial or viral pathogenic molecule (a so-called antigen) is detected, an antibody neutralizes it by binding to it. However, autoantibodies are sometimes produced against […]

February 21, 2019

As such, identifying new biomarkers has become an increasing focus in 21st century drug discovery and development, and the inclusion of molecular markers in clinical trial design allows for the retrospective analysis of data and the identification of patient sub-groups […]

February 8, 2019

During the research, the team examined the markers related to the blood-brain barrier, which regulates the movement of cells and molecules between the blood and the fluid that surrounds the brain nerve cells. In more than 160 people with and […]

January 31, 2019

The study showed that the tongue-coating microbiomes of patients with early-stage pancreatic were significantly more diverse and composed of remarkably different bacteria, compared with the tongue coatings of healthy individuals. Pancreatic cancer is the seventh leading cause of cancer-related death […]

January 8, 2019

This makes it the third most common cancer that medical professionals detect in both men and women. Colorectal cancer, which doctors also refer to as bowel cancer, is responsible for more than 50,000 deaths each year in the U.S. If […]

January 7, 2019

The research was conducted by scientists from the Institute of Cardiovascular Sciences and the Institute of Cancer and Genomic Sciences. The team found that older male patients with a high body mass index are at a higher risk of atrial […]

November 28, 2018

A technique to get more information from the blood of cancer patients than previously possible has been developed. The discovery could potentially accelerate early diagnosis, speed up drug discovery and lead to advancements in personalized medicines. The Cancer Research UK-funded […]

November 12, 2018

The alliance will use Oxford BioDynamics’ EpiSwitch high-throughput technology to develop a biomarker assay for the blood-based diagnosis of the neurodevelopmental condition. EpiSwitch is designed to enable the discovery, evaluation, validation and monitoring of a new type of epigenetic biomarkers […]

November 6, 2018

The majority of infected patients do not show symptoms or have mild illness with low-grade fever. However, foetuses exposed to the virus are at risk of neurological defects, including microcephaly. The team expects the latest finding to help in developing […]

November 2, 2018

This breakthrough finding could result in a diagnostic test to screen fetuses for Zika-associated birth defects whilst still in the womb. This would reassure expectant mothers that their babies are healthy. The Zika virus is transmitted by the bite of […]

November 2, 2018

Researchers have elucidated the disease risk underlying a biomarker predictive of shorter lifespan. Researchers have been able to unravel the disease burden that underlies increased mortality risk for and all-cause mortality biomarker they discovered in 2014. They found, that low-level […]

October 29, 2018

They used magnetic brainwave imaging to correlate altered gamma oscillation with the motor response of children with ASD. This is consistent with previous key hypotheses on the disease that autism results from an excitatory and inhibitory imbalance in the brain, […]