Coronavirus disease 2019 (COVID-19) is a viral infection caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This disease caused the most severe pandemic of this century, with almost 150 million documented infections, over three million deaths, and is still devastating many countries with successive waves of infection.
In the absence of any specific and effective antiviral, the primary intervention that may bring an end to the pandemic is vaccination. More than a score of newly developed vaccines against COVID-19 have been rolled out, all over the world, following emergency use authorization. Tens of millions of doses have been administered.