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SARS-CoV-2 RNA can be reverse-transcribed to be part of chimeric viral-human genome

December 16, 2020

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As the coronavirus disease 2019 (COVID-19) pandemic continues to take its toll on human life and economic activity, reports have emerged about the repeated positive tests and continued shedding of the virus for weeks and months after clinical recovery.

A study appearing as a preprint on the bioRxiv* server in December 2020 reveals that the genome of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is inserted into the human genome, accounting for the detection of viral RNAs, even in late convalescence.

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