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Researchers discover intake of FDA-approved drug modulates disease progression in Alzheimer’s disease model

March 24, 2022

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Indiana University School of Medicine researchers found that niacin limits Alzheimer’s disease progression when used in models in the lab, a discovery that could potentially pave the way toward therapeutic approaches to the disease.

The study, recently published in Science Translational Medicine, investigates how niacin modulates microglia response to amyloid plaques in an Alzheimer’s disease animal model.

Gary Landreth, PhD, Martin Professor of Alzheimer’s Research, and Miguel Moutinho, PhD, postdoctoral fellow in Anatomy, Cell Biology and Physiology, led the study.

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