It is well known that fat cells can influence our sensitivity to insulin. Now, researchers at Karolinska Institutet in Sweden have discovered that there are three different subtypes of mature fat cells in white adipose tissue and that it is only one of these, called AdipoPLIN, that responds to insulin. The findings may be relevant for future treatments of metabolic diseases such as Type 2 diabetes.
“These findings increase our knowledge about the function of fat tissue,” says co-corresponding author Niklas Mejhert, researcher at the Department of Medicine, Huddinge, at Karolinska Institutet.