Researchers at the University of Eastern Finland have uncovered potential mechanisms by which microRNAs (miRNA) drive atherogenesis in a cell-type-specific manner. Published in the Arteriosclerosis, Thrombosis, and Vascular Biology journal, the study provides novel insight into the miRNA profiles of the main cell types involved in atherosclerosis.
Atherosclerosis is the underlying cause of most cardiovascular diseases and one of the leading causes of mortality in the world. During atherosclerosis, arteries become progressively narrow and thick due to the formation of plaques containing cholesterol deposits, calcium and cells, among other components.
