Much of the current discussion on reducing the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has wrongly focused on the effectiveness of individual interventions, especially vaccination.
As new virus variants emerge, with increased transmissibility and immune evasion properties, it seems indubitable that various protective measures must be combined to achieve a synergistic effect on viral transmission and prevent future surges of coronavirus disease 2019 (COVID-19). These include vaccination, universal mask use, and social distancing, as well as ventilation of indoor spaces and testing and isolation of symptomatic contacts and suspected/confirmed cases, respectively.
