Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causal agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic, is an RNA virus belonging to the family Coronaviridae. This virus is highly virulent with a greater transmission rate and causes mild to severe symptoms. This virus has infected around 238 million individuals and claimed more than 4.8 million lives worldwide.
Background
Several COVID-19 vaccines have been developed, and many have received emergency use authorization (EUA). In the majority of countries across the world, vaccination programs have been initiated. Owing to the emergence of SARS-CoV-2 variants due to genomic mutations, the efficacy of the approved vaccines is in question.