Cerebral cavernous malformations (CCM) are the most common cause of stroke in young people. These malformations also known as Cavernomas are present in 0.1-0.5% of the population, with about 60% causing symptoms. Currently there is no drug treatment available for CCM.
However, as opposed to stroke in the elderly where no single genetic defect is implicated, in CCM defect in one of three genes (CCM1, CCM2 and CCM3) causes CCM disease.
