One example of a complex autoimmune disease is systemic lupus erythematosus (SLE), which predominantly affects women. As the disease progresses, the body’s own immune system attacks the skin, blood vessels and internal organs such as the kidneys. Early intervention is important to prevent severe organ damage. Treatment options include suppressing the body’s immune system as well as more targeted therapies, such as removing autoreactive cells. However, until now it has remained unclear how the timing of the various types of treatment would affect the later progression of the disease.
