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A new atlas of cells that carry blood to the brain

February 15, 2022

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While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen and other nutrients to the brain.

Those cells, which comprise only 0.3 percent of the brain’s cells, also make up the blood-brain barrier, a critical interface that prevents pathogens and toxins from entering the brain, while allowing critical nutrients and signals through. Researchers from MIT have now performed an extensive analysis of these difficult-to-find cells in human brain tissue, creating a comprehensive atlas of cerebrovascular cell types and their functions.

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