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New method for stimulating signaling to improve metabolic health and possibly treat obesity

February 14, 2022

Following up on a 2018 study that identified an epigenetic modifier known as histone deacetylase 11 (HDAC11) as a potential therapeutic target for treating obesity and diabetes, researchers from the University of Colorado School of Medicine have published new research that finds HDAC11 regulates G protein-coupled receptors (GPCRs) called beta-adrenergic receptors (β-ARs).

The details of the study are published in the Proceedings of the National Academy of Sciences of the United States of America (PNAS), the official journal of the National Academy of Sciences.

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