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Structural and molecular contributions to understanding antibody recognition of pathogenic viruses

November 1, 2021

Viral infections may have enormous global impacts, as evidenced by the recent coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). History has many other examples, such as the Ebola epidemics of 2013- 2016, the H1N1 pandemic of 2009-2010, etc. Structural biology aims to determine how antibodies elicited during infection or vaccination target viral proteins. A new review published in Viruses reviews how molecular and structural biology have contributed to our understanding of antibody recognition of HIV-1, SARS-CoV-2, and Zika.

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