May 26, 2022
Via: ScienceDailyCRISPR has ushered in the era of genomic medicine. A line of powerful tools has been developed from the popular CRISPR-Cas9 to cure genetic diseases. However, there is a last-mile problem — these tools need to be effectively delivered into […]
April 8, 2022
Via: ScienceDailyUNSW researchers have used CRISPR gene editing — a type of ‘molecular scissors’ — to understand how deletions in one area of the genome can affect the expression of nearby genes. The work, led by UNSW Associate Professor Kate Quinlan […]
May 3, 2021
Via: The Medical NewsUT Southwestern scientists successfully employed a new type of gene therapy to treat mice with Duchenne muscular dystrophy (DMD), uniquely utilizing CRISPR-Cas9-based tools to restore a large section of the dystrophin protein that is missing in many DMD patients. The […]
September 25, 2020
Via: The Medical NewsA new study conducted by researchers at the University of Eastern Finland found that the PLCG2-P522R genetic variant, which protects against Alzheimer’s disease, enhances several key functions of immune cells. The results obtained in the study highlight the importance of […]
March 30, 2020
Via: The Medical NewsResearchers at Karolinska Institutet and St Erik Eye Hospital in Sweden have discovered a way to refine the production of retinal cells from embryonic stem cells for treating blindness in the elderly. Using the CRISPR/Cas9 gene editing, they have also […]
February 26, 2020
Via: The Medical NewsThe standard gene-editing tool, CRISPR-Cas9, frequently produces a type of DNA mutation that ordinary genetic analysis misses, claims new research published in the journal Proceedings of the National Academy of Sciences (PNAS). In describing these findings the researchers called such […]
September 17, 2019
Via: The Medical NewsCRISPR technology has greatly facilitated gene editing. Associate Professor Thorsten Müller from Ruhr-Universität Bochum and Dr. Hassan Bukhari from Harvard Medical School discuss its pros and cons in a review article in the journal “Trends in Cell Biology” from 12 […]
August 6, 2019
Via: Time HealthIt’s only been seven years since scientists first learned how to precisely and reliably splice the human genome using a tool called CRISPR, making it possible to think about snipping out disease-causing mutations and actually cure, once and for all, […]
May 28, 2019
Via: The Medical NewsScientists at Fred Hutchinson Cancer Research Center took a step toward making gene therapy more practical by simplifying the way gene-editing instructions are delivered to cells. Using a gold nanoparticle instead of an inactivated virus, they safely delivered gene-editing tools […]
December 13, 2018
Via: The Medical NewsCRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a recently discovered gene-editing technology that utilizes the bacterial innate immune system to detect specific regions of the genome using an RNA template. The enzyme, Cas9, is directed to the target where […]
July 12, 2018
Via: The Medical NewsResearchers at Brigham and Women’s Hospital have engineered cancer cells that track and kill cancer cells. The modified cancer cells have demonstrated anti-cancer efficacy in preclinical studies, destroying both primary and metastatic tumours. Each year over 8 million people die […]
January 5, 2018
Via: The Medical NewsAn urgent question for cancer scientists is why immunotherapy achieves dramatic results in some cases but doesn’t help most patients. Now, two research groups from Dana-Farber Cancer Institute have independently discovered a genetic mechanism in cancer cells that influences whether […]
August 11, 2017
Via: Kelly RedmondBiotech companies that operate in genome editing are on a rush to keep pace with the way this technology is gaining momentum. Although the core of this genetic engineering technique is still highly disputable from an ethical point of view, […]