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Tag: Compound


Innovation, Research

Research examines the effectiveness of various oral hygiene tools

September 30, 2021

Via: The Medical News

Do probiotics prevent gum disease? Is flossing necessary? Many patients are unable to confidently answer these questions and more due to the abundance of conflicting medical information. However, new research led by the University at Buffalo aims to separate fact […]


Innovation, Research

Research identifies SARS-CoV-2 cavities as potential drug targets

June 21, 2021

Via: The Medical News

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein has been the main target for the development of vaccines and other therapeutics needed to treat COVID-19 illness. New research published in the journal Future Medicine found the SARS-CoV-2 spike […]


Innovation, Research

Virtual analysis identifies a potential natural inhibitor of SARS-CoV-2 Nsp15

May 19, 2021

Via: The Medical News

Coronavirus disease 2019 (COVID-19) is a viral infection caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This disease caused the most severe pandemic of this century, with almost 150 million documented infections, over three million deaths, and is […]


Innovation, Research

New drug-like compound could effectively block a critical step in malaria parasite life cycle

May 12, 2021

Via: The Medical News

Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a critical step in the malaria parasite life cycle and are working to develop this compound into a potential […]


Innovation, Research

The use of mammalian cell surface display for rapid characterization of SARS-CoV-2 variants

April 5, 2021

Via: The Medical News

A research group from the U.S. demonstrated the practicality of a spike display system in order to accelerate vaccine design, but also to swiftly appraise the effects of mutations in emerging strains of the severe acute respiratory syndrome coronavirus 2 […]


Innovation, Research

Comparative study of SARS, MERS, BAT‐SARS, and SARS-CoV-2

April 2, 2021

Via: The Medical News

Scientists have found that several viruses which belong to the Coronaviridae family can infect a wide range of hosts, including birds, humans, and other mammals. These viruses are single-stranded, positive-sense, RNA viruses whose size ranges between 27-32 kb. They are […]


Innovation, Research

Researchers uncover potential glycine-based treatment for NAFLD

December 3, 2020

Via: The Medical News

A new study further implicates low levels of the amino acid glycine in development of nonalcoholic fatty liver disease, or NAFLD. It also suggests addressing this might hold the key to a future treatment for the disease. “We’ve uncovered a […]


Innovation, Research

Potential SARS-CoV-2 antiviral: Ionophore X-206 found to inhibit viral replication in cell cultures

December 1, 2020

Via: The Medical News

One of the efforts to combat the ongoing coronavirus disease 2019 (COVID-19), pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is repurposing drugs already in use. Polyether ionophores are a family of natural products used as antibiotics. […]


Biomarker, Innovation

Novel molecules show potential for future cancer therapies

November 3, 2020

Via: The Medical News

Cancers sometimes escape our immune defenses because of the over-activity of molecular signaling systems, called checkpoint processes. Now we may be able to fight back using a new range of molecules, researchers in China report in the European Journal of […]


Innovation, Research

Researchers create drug-like compounds to destroy coronavirus’ frameshifting element

September 30, 2020

Via: The Medical News

Scripps Research chemist Matthew Disney, PhD, and colleagues have created drug-like compounds that, in human cell studies, bind and destroy the pandemic coronavirus’ so-called “frameshifting element” to stop the virus from replicating. The frameshifter is a clutch-like device the virus […]


Innovation, Research

Researchers identify a potential drug candidate for hand, foot and mouth disease

September 22, 2020

Via: The Medical News

A study appearing next week in the journal Nature Communications offers some good news in the search for antiviral drugs for hard-to-treat diseases. Researchers have identified a potential new drug candidate against enterovirus 71, a common cause of hand, foot […]


News

Researchers identify potential anti-viral strategy for SARS-CoV-2 virus

July 29, 2020

Via: The Medical News

In the case of an infection, the SARS-CoV-2 virus must overcome various defense mechanisms of the human body, including its non-specific or innate immune defense. During this process, infected body cells release messenger substances known as type 1 interferons. These […]


Innovation, Med Tech

New technology could speed up drug discovery to fight tuberculosis

July 23, 2020

Via: The Medical News

A new technology that combines high throughput imaging and machine learning could speed discovery of drugs to fight tuberculosis, which for generations has killed more people worldwide than any other disease caused by a single agent-;4,000 people every day. Current […]


Innovation, Research

Researchers modify nanoparticles to improve their uptake in gastrointestinal tract

August 9, 2018

Via: The Medical News

Nanoparticles show great promise as diagnostic tools and drug delivery agents. The tiny particles, which scientists can modify with drugs, dyes or targeting molecules, can travel in the circulation and squeeze through small spaces into cells and tissues. But until […]


Innovation, Research

Researchers discover novel antibiotic from leaf of common weed

July 27, 2018

Via: The Medical News

Many of the antibiotics used today were developed from natural products made by bacteria themselves in order to ward off other bacteria. These products used to be sought and found primarily in soil. Now, Julia Vorholt and Jörn Piel of […]


Innovation, Research

Researchers take step toward using man-made nanoscale compounds to fight cancer

December 13, 2017

Via: The Medical News

Researchers in Sweden have succeeded in taking the next step toward using man-made nanoscale compounds in the fight against cancer. A recent proof-of-concept study showed that dendrimers – which were first introduced in the 1980s – may be used to […]