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Not Everyone Needs a Second COVID Booster

March 21, 2022

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Last week, both Pfizer and Moderna applied for emergency use authorization (EUA) of additional booster doses — in essence, fourth doses — of their COVID-19 vaccines. The companies cite waning protection and believe fourth doses are needed. While Pfizer has asked for an EUA focused on those above 65 years old, Moderna is seeking one applicable to all adults. It is critical, as we debate COVID-19 vaccine clinical guidance, to be explicit about the goals we are trying to achieve.

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