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US researchers develop test for DNA damage by chemical compounds

December 6, 2017

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Researchers at Georgetown Lombardi Comprehensive Cancer Centre in the US have developed a new biomarker test, TGx-DDI, to accurately identify and predict chemical compounds that could cause DNA damage leading to cancer.

TGx-DDI biomarker panel is based on actively transcribed or expressed genes, which reflect certain pathways responding to different stress types and provide information on cell response to injury such as DNA damage.

The new test is designed to address the concerns with current expensive and time-consuming laboratory tests that are reported to yield more false-positive findings for agents that could cause DNA damage.

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