The prevalence of using antidepressants and proton pump inhibitors increases after the diagnosis of Alzheimer’s disease, according to a doctoral dissertation from the University of Eastern Finland. The use of antidepressants was associated with an increased risk of hip fracture among persons with and without Alzheimer’s disease. The use of proton pump inhibitors, however, did not increase the risk of hip fracture even in the long term. The study also found that the concomitant use of acetylcholinesterase inhibitors and urinary antispasmodics was prevalent among persons with Alzheimer’s disease, even though the concomitant use of these drugs is not recommended due to their opposite pharmacological mechanisms.
