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SARS-CoV-2 nucleocapsid antigen as a possible COVID-19 severity marker

September 30, 2021

Coronavirus disease (COVID-19) has been the focus of molecular research over the past 18 months. Despite the efforts behind the development of vaccines against the severe acute respiratory distress syndrome coronavirus (SARS-CoV-2), the relationship and dynamics between host and viral proteins and their impact on disease severity remain unclear.

Studies focusing on viral antigenic load in respiratory fluids have shown a high concentration of viral RNA in the initial phase, followed by a rapid decrease in the second week after the onset of symptoms and a low or undetectable level of RNA later.

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