Researchers from Laval University and McMaster University in Canada have studied the use of polygenic risk score in predicting early-onset of heart disease.
Based on multiple genetic differences, the risk score or polygenic test is reported to have identified more cases compared to conventional tests that screen for single genetic defects.
Early diagnosis and treatment are considered critical for patients with a rare genetic defect called familial hypercholesterolemia (FH), as they are reported to be at high risk for early onset of the disease.
