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Researchers discover new details of brain pathway related to impulsive behaviors

January 25, 2019

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Researchers from Singapore and South Korea have uncovered new details of a brain pathway that can cause impulsive behaviors.

Using mice, the research team led by Professor George Augustine from Nanyang Technological University, Singapore (NTU Singapore), discovered that impulsive behavior is triggered when the brain signaling chemical dopamine is passed to an unexpected area of their brain.

The full route that dopamine signals take to produce an impulsive action has not previously been understood. To trace its pathway, Prof Augustine and his team used mice that had a specific set of dopamine receptors (“D2 receptors”) genetically removed, effectively making their brains unable to detect dopamine signals.

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