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Researchers discover new biomarker for postoperative liver dysfunction

March 18, 2019

There is an urgent need for an easily accessible preoperative test to predict postoperative liver function recovery and thereby determine the optimal timing of liver resection, particularly since the currently available methods are either costly, time-consuming or invasive.

For several years now, the groups led by Patrick Starlinger from MedUni Vienna’s Department of Surgery and Alice Assinger from MedUni Vienna’s Center for Physiology and Pharmacology have focused on the prediction of postoperative liver dysfunction and clinical outcomes that can be expected following liver resection. MicroRNA signatures represent a new approach in this research and are already known as potent diagnostic, prognostic and treatment response biomarkers for many different diseases.

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