As reported in the journal ChemMedChem, Prasanthi Medarametla and colleagues have targeted a protein called LsrK that is involved in a bacterial communication process called quorum sensing.
Quorum sensing enables bacteria to colonize, produce virulence factors, form a biofilm and to establish infection.
Disrupting the process of quorum sensing has therefore become a new focus in the investigation of agents that may quench and inhibit bacteria.
