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Researchers challenge conventional understanding of cause of Parkinson’s

June 26, 2019

Parkinson’s disease is one of the most common neurodegenerative diseases worldwide. This disease is typically accompanied by motor defects such as the tremor of arms and legs, slowness of movements and muscle rigidity, which occur together with other non-motor symptoms. A characteristic of this progressively worsening and currently unstoppable disease are neuronal inclusions, so called Lewy bodies, that occur in many regions of the brain in the course of the disease. For decades, it was assumed that Parkinson’s disease is caused by deposits of insoluble fibrils consisting of the protein alpha-synculein in the Lewy bodies.

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