T cells, biology textbooks teach us, are the soldiers of the immune system, constantly on the ready to respond to a variety of threats, from viruses to tumors. However, without rest and maintenance T cells can die and leave their hosts more susceptible to pathogens, Yale scientists report May 27 in the journal Science.
“We may have to change how we teach T cell biology,” said Lieping Chen, the United Technologies Corporation Professor in Cancer Research at Yale and professor of immunobiology, of dermatology, and of medicine and senior author of the study.