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Proteomics shows SARS-CoV-2 NSP7 and NSP8 forms stable dimeric unit

March 9, 2021

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Coronavirus disease 2019 (COVID-19), caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has claimed over 2.6 million lives worldwide. Despite significant gains in scientific research since the onset of the pandemic in late-2019, much remains to be known about this virus and its biology.

A new preprint, released on the bioRxiv* preprint server, describes the structure of part of the dynamic protein-RNA complex known as the replication-transcription complex (RTC), which is crucial in the replication of the large ribonucleic acid (RNA) genome of this virus.

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