The phase 3 trials of the Pfizer and Moderna coronavirus disease 2019 (COVID-19) vaccines did not include those with a known previous severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Recent evidence indicates that mRNA vaccines may induce more adverse events in these individuals. In a paper recently uploaded to the medRxiv* preprint server, 947 individuals, 265 of which have previously reported SARS-CoV-2 infection, were monitored post-vaccination for adverse events, finding that there could be a link between previous infection and greater incidence of these events.
