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Monitor Bone Health With High-Dose Topical Corticosteroids

January 20, 2021

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Potent topical corticosteroids were associated with increased risk for osteoporosis, a Danish study suggested.

In a nationwide retrospective cohort study of over 720,000 adults, each doubling in cumulative dosing of potent and very potent topical corticosteroids — commonly used for chronic skin conditions like atopic dermatitis and psoriasis — raised the relative risk for development of osteoporosis by 3% (95% CI 2%-4%), reported Alexander Egeberg, MD, PhD, of the University of Copenhagen, and colleagues.

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