Common immunization routes for coronavirus disease 2019 (COVID-19) vaccine candidates range from intramuscular, nasal and oral to intradermal.
Now, scientists at the University of Salzburg and Pantec Biosolutions AG have developed a laser-facilitated epicutaneous immunization against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein. The model has induced angiotensin-converting enzyme 2 (ACE2) blocking antibodies in mice.
The study, published on the pre-print bioRxiv* server, shows another potential effective route to administer vaccines against SARS-CoV-2, the virus that causes COVID-19. Finding more ways to introduce vaccines can help combat the pandemic.
