The study focuses on cells in the meniscus, which is a thin layer of dense connective tissue in the human knee. However, the approach could prove effective beyond that specific area.
“In this case, we studied how meniscus cell nuclei can be softened to promote their migration through meniscus tissues. We have also shown similar enhancement of cell migration in other types of connective tissues, such as tendons or the cartilage covering the ends of bones,” said the study’s first author, Su Chin Heo, PhD, an assistant professor of research of Orthopaedic Surgery, who works within the McKay Orthopaedic Research Lab.
