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New mechanism that could counteract obesity

September 4, 2019

Lead author Alessandro Bartolomucci, PhD, Associate Professor in the Department of Integrative Biology and Physiology at the U of MMedical School, and his team, which includes first author Bhavani Sahu, PhD, and Yuk Sham, PhD, U of M Medical School, discovered that critical mutations in a peptide and a receptor, which are known to be implicated in obesity, diabetes, and hypertensions in rodents, are critical for these biological activities. The findings, published in Cell Reports, suggest a new possible therapeutic approach to human disease.

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