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New discovery opens more opportunities in Alzheimer’s treatment with vaccines

Alzheimer’s disease (AD) is a complex and poorly understood disorder that ultimately leads to neurodegeneration in patients afflicted with the disease. The pathophysiology of AD is still unknown; however, some scientists believe that viruses play a role in the development of AD, as demonstrated in a recent study.

In a study published in the June 21 issue of the journal Neuron, researchers analyzed data from postmortem brain tissue samples of people with and without AD, finding increased levels of the two Roseoloviruses, human herpesvirus 6A (HHV-6A) and human herpesvirus 7 (HHV7), demonstrating the theory that viruses may have a role in AD biology. However, researchers believe that the viral mechanisms could generate the disease but not be a main cause in AD progression.