Researchers at the Massachusetts Institute of Technology (MIT) in the US have developed a computational model to improve the injectability of microparticles and prevent clogging during injections.
The model determines an optimal design for injectability by analysing a variety of factors such as the size and shape of the particles, particle concentration in the solution, viscosity of the solution and needle size.
Microparticles, which range in size from 1 to 1,000 microns, are used to deliver multiple doses of a drug or vaccine at once. However, they are considered difficult to inject due to their tendency to get clogged in typical syringes.
