New research published in the International Journal of Pharmaceutics demonstrates that ‘good’ bacteria in the live probiotic SymproveTM can successfully reach and colonize the gut, where they go on to change the existing gut flora. They are also capable of modifying immune response.
Researchers found that all bacteria in Symprove survived the stomach acid to reach and colonize the gut. The activity of the bacteria in this study were observed using a novel Simulator of the Human Intestinal Microbial Ecosystem (SHIME) and used donor bacteria from healthy humans. This allows researchers to closely monitor bacteria through in-vitro simulation of the human gut, without the need for invasive procedures and measurements.