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Human protein plays key role in transcription and genome integrity

June 4, 2020

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Researchers from the University of Seville and Cabimer discover that the UAP56/DDX39B protein remove DNA-RNA hybrids from the genome

Transcription of genetic information is a fundamental process for life. If it does not work correctly, the consequences for the organism range from lethality to defects during development, genetic diseases, insufficient response to infections and stresses or propensity to develop cancer, given its pleiotropic effect. For this reason, it is important to know in depth the process by which this “DNA copy” is obtained and what elements are involved.

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