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Human genetics evidence predictive of drug development success, study shows

December 13, 2019

A new drug candidate is more likely to be approved for use if it targets a gene known to be linked to the disease; a finding that can help pharmaceutical companies to focus their drug development efforts. Emily King and colleagues from AbbVie report these findings in a new study published 12th December in PLOS Genetics.

Only 5 to 10 percent of potential new drugs that enter early stage clinical trials are ultimately approved, and this low success rate increases the cost of development for all new drugs.

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