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Driving bacteria to produce potential antibiotic, antiparasitic compounds

June 25, 2020

The researchers wanted to overcome a decades-old problem that confronts those hoping to study and make use of the countless antibiotic, antifungal and antiparasitic compounds that bacteria can produce, said Satish Nair, a University of Illinois at Urbana-Champaign professor of biochemistry who led the research.

“In laboratory conditions, bacteria don’t make the number of molecules they have the capability of making,” he said. “And that’s because many are regulated by small-molecule hormones that aren’t produced unless the bacteria are under threat.”

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