A discovery about how human cells are ‘triggered’ to undergo an inflammatory type of cell death could have implications for treating cancer, stroke and tissue injury, and immune disorders.
A research team from the Walter and Eliza Hall Institute in Melbourne identified the molecular trigger in human cells that drives necroptosis, and implicated defects in this molecular trigger as potentially playing a role in cancer development.
The research, published today in Nature Communications, was led by Institute researchers Dr Emma Petrie, Dr Jarrod Sandow and Associate Professor James Murphy.
