Researchers at Ruhr-Universität Bochum (RUB) have studied the role of the immune response in the development of glaucoma in mice. They showed that inflammatory processes are associated with the pathogenesis of the disease and that the extracellular matrix molecule tenascin-C plays a key role as a modulator of the immune response. Glaucoma is a common cause of blindness worldwide. Typically, intraocular pressure is increased in patients, but in around 40 per cent it stays in normal ranges. The results on the role of the immune response were published online on 9 October 2020 in the journal Frontiers in Immunology.