About 10% of survivors of adult-onset first primary cancers were diagnosed with a subsequent primary cancer (SPC), researchers reported.
Smoking-related SPCs accounted for 25% to 45% of the total SPC incidence and mortality, and obesity-related SPCs accounted for about one-quarter of total SPC mortality, according to Ahmedin Jemal, DVM, PhD, of the American Cancer Society in Atlanta, and colleagues, writing in JAMA.
They looked at data from 12 Surveillance, Epidemiology, and End Results (SEER) registries that included 1.53 million people diagnosed with a first primary cancer from 1992 to 2011 and who survived at least 5 years, and estimated the increased risk for SPC using standardized incidence ratio (SIR) and standardized mortality ratio (SMR) versus the general population, the authors explained.
