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Blood clotting proteins in urine act as potent biomarkers for lupus

August 7, 2019

Researchers have discovered that blood clotting proteins in urine can act as biomarkers in patients with systemic lupus erythematosus (SLE), especially those with lupus nephritis.

The team of researchers at the University of Houston found that blood clotting proteins, both the ones that promote blood clotting (prothrombic) and those that disperse them (thrombolytic) are elevated in the urine of patients with lupus nephritis (LN).

Published in the journal Arthritis Research & Therapy, the study shows that among the proteins tested, urine plasmin has shown the greatest independent predictor of kidney function and renal disease status.

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