Tag: mutations

June 20, 2022

Cancer cells can have thousands of mutations in their DNA. However, only a handful of those actually drive the progression of cancer; the rest are just along for the ride. Distinguishing these harmful driver mutations from the neutral passengers could […]

June 13, 2022

For many years, the human genome was viewed as a book of life in which sections of great eloquence and economy of expression were interspersed with vast stretches of gibberish. The legible sections contained the code for making cell proteins; […]

February 9, 2022

Researchers led by bioengineers at the University of California San Diego have identified and characterized a previously unrecognized key player in cancer evolution: clusters of mutations occurring at certain regions of the genome. The researchers found that these mutation clusters […]

December 6, 2021

Lymphoma, a type of blood cancer, is the fifth most common cancer among males and the sixth most common cancer for females in Singapore, according to latest data from the Singapore Cancer Registry.Broadly divided into Hodgkin lymphoma and non-Hodgkin lymphoma, […]

October 20, 2021

The ability to edit the genome by altering the DNA sequence inside a living cell is powerful for research and holds enormous promise for the treatment of diseases. However, existing genome editing technologies frequently result in unwanted mutations or can […]

August 20, 2021

A new study published on the preprint server bioRxiv* describes how monoclonal antibodies raised against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are affected by mutations in the antibody binding site. This finding could help design newer and better […]

July 28, 2021

Upon first inspection, the mutations in the highly contagious delta covid variant don’t look that worrisome. For starters, delta has fewer genetic changes than earlier versions of the coronavirus. “When people saw that the epidemic in India was driven by […]

April 2, 2021

There have been concerns that several severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have mutations that allow them to evade the immune system. A new study published in the Open Forum Infectious Diseases suggests otherwise. Led by Aaron AR […]

March 30, 2021

Mutations of the coronavirus could render current vaccines ineffective within a year, according to a majority of epidemiologists, virologists and infectious disease specialists surveyed by the People’s Vaccine Alliance. The survey of 77 experts from some of the world’s leading […]

March 9, 2021

Schizophrenia is a neurodevelopmental disorder that disrupts brain activity producing hallucinations, delusions, and other cognitive disturbances. Researchers have long searched for genetic influences in the disease, but genetic mutations have been identified in only a small fraction — fewer than […]

August 4, 2020

Researchers from IRB Barcelona’s Genome Data Science Lab, led by the ICREA researcher Fran Supek, have discovered a new type of hypermutation called mutation fog, which can generate hundreds of mutations in every cell. Such mutations are widely distributed, but […]

February 6, 2020

The gold nanoparticle-based probe measures viral RNA in live influenza A cells, according to a study in The Journal of Physical Chemistry C. It is the first time in virology that experts have used imaging tools with gold nanoparticles to […]

September 20, 2019

DENV2 exists as smooth spherical surface particles while growing at the mosquito’s physiological temperature (29 degrees Celsius). It then changes to bumpy surfaced particles at human physiological temperature (37 degrees Celsius). This ability to morph helps the virus to evade […]

September 4, 2019

Lead author Alessandro Bartolomucci, PhD, Associate Professor in the Department of Integrative Biology and Physiology at the U of MMedical School, and his team, which includes first author Bhavani Sahu, PhD, and Yuk Sham, PhD, U of M Medical School, […]

January 10, 2018

While the exact cause of Parkinson’s disease is unknown, the development of the condition is influenced by many genetic and environmental factors. Doctors have identified how mutations in some genes can be passed down through generations and may lead to […]