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Watching gene editing at work to develop precision therapies

January 25, 2017

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University of Wisconsin-Madison engineers have developed methods to observe gene editing in action, and they’re putting those capabilities to work to improve genetic engineering techniques. “Ultimately, the knowledge we gain from this project has the potential to set the foundation for new preclinical platforms in precision medicine,” says Krishanu Saha, an assistant professor of biomedical engineering at UW-Madison and the principal investigator on the project.

A new technique called CRISPR-Cas9 gives researchers the ability to make changes to the DNA of, theoretically, any living organism that has DNA. “CRISPR-Cas9 lets researchers rewrite the genome in a very precise manner,” says Saha.

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