The findings, which were recently published in the journal Immunity, could pave the way for new approaches to reducing transplant rejection in the future.
Organ transplant rejection occurs when immune cells called T cells respond to donor organs as if they were foreign invaders such as viruses, bacteria and fungi.
Now, Jean Pieters and colleagues have found a way to selectively suppress this reaction to donor organs by modulating a protein regulator of T cells called coronin 1.
