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Engineering non-immune cells to kill cancer cells

November 13, 2017

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T-cells are one of the immune system’s major weapons. They detect the body’s cells infected with a virus and trigger their ablation, effectively killing the virus. T-cells cannot do the same with cancer cells, however, as they do not recognise them as foreign cells and are therefore unable to eliminate them.

But researchers have recently used T-cells engineered in the laboratory to combat tumours. Modified to include additional functions, these immune cells can hunt down and kill cancer cells. Unfortunately, however, such immune cell therapies can have significant side-effects. On top of that, the production of modified T-cells is technically challenging.

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